SightsThere are a surprising number of sights in Pisa aside from the obvious Leaning Tower. Make sure you visit the Duomo di Pisa, Battistero, Campo Santo Monumentale, Museo del Opera del Duomo, Museo delle Sinopie, Palazzo della Carovana, Palazzo dell'Orologio, Chiesa di Santo Stefano among many other sights.
NeighborhoodsPisa was first settled on the northern shore of the river Arno. Today's city center is divided into two major districts and four historical quarters. Santa Maria, San Francesco, Sant' Antonio and San Martino are in the area enclosed by the 12th century city walls.
The Piazza dei Miracoli, or Field of Miracles is in the northern part of the city. It's a UNESCO World Heritage site and where many tourists spend the majority of their time. It is also where you'll find the Leaning Tower.
ActivitiesThe Luminara Festival is a popular event in the city. It's held on June 16th for patron saint's day. At sunset the lights along the Arno dim and there are more than 10,000 candles lit. It's an impressive sight and worth visiting if you're in town. Gioco del Ponte is another summer event. It's held the last Sunday of June and is a historical reinactment of a procession and competition. Because of the active student body, there is also no shortage of nightlife around town. Clubs and music are abundant and active during the school year.
Food and DiningAs with most touristy towns, it is best to go outside of the main tourist sections to find a restaurant. In particular, avoid eating near the Leaning Tower as the quality of the food is low and the prices are quite high. Instead, make your way to the central part of town which is about a five or ten minute walk from Piazza di Miracoli. The restaurants in the area are affordable and good. You'll find many reasonably priced cafeterias near the vegetable market in Piazza delle Vettovaglie. Another great area to eat is Via San Martino near the south bank of the river. Prices here are also low, but the food is fresh and good.
If you do want to eat near the Leaning Tower then there's a decent Indian Restaurant in Via Roma. A restaurant style pizzeria called Kinzica is also located in Piazza dei Miracoli. It's reasonably affordable and decent quality. For chocolates and sweets go to Salza, in Borgo Stretto. Although the prices are high, they are a special treat that you shouldn't miss.
TransportationIt's easy to reach Pisa from Florence by train. There are about three connections an hour and there are also hourly connections to Lucca. Regular buses also make the trip. The main train station in town is Pisa Centrale. There you will find a left luggage service that is open from 6 am to 9 pm. This is convenient if you are passing through the city in route to another place. If you're coming to town specifically to see the Tower then you can take the train to the Pisa S. Rossore train station that is more conveniently located closer to the Tower. Make sure that your specific train stops at this station, as not all do.
Once you're in town there is a convenient and efficient bus system. Buses connect the train station to the Field of Miracles and most attractions can easily be walked to in about a half an hour. You can buy bus tickets at local tobacco shops or from vendoring machines that are found in the stations and at the airport. If you're hoping to travel around Tuscany in a private car, then there are many rental car agencies at the airport. You'll need to take a shuttle bus from the airport to the rental offices though. This shuttle can be caught near the airport's arrival hall by the city bus stop. You do not need a car within the city, but a private vehicle can make off the beaten path excursions more convenient elsewhere in Tuscany.